Are medication alerts useless since most clinicians override them anyway?

Are medication alerts useless since most clinicians override them anyway?

A February 2009 internal medicine study entitled “Overrides of Medication Alerts in Ambulatory Care” concludes the following:

Clinicians override most medication alerts, suggesting that current medication safety alerts may be inadequate to protect patient safety.

In my work I have certainly seen many alerts constantly being overridden but I didn’t realize how big an issue it was until I read this article. Here’s what else they said:

Background Electronic prescribing systems with decision support may improve patient safety in ambulatory care by offering drug allergy and drug interaction alerts. However, preliminary studies show that clinicians override most of these alerts.

Methods We performed a retrospective analysis of 233 537 medication safety alerts generated by 2872 clinicians in Massachusetts, New Jersey, and Pennsylvania who used a common electronic prescribing system from January 1, 2006, through September 30, 2006. We used multivariate techniques to examine factors associated with alert acceptance.

Results A total of 6.6% of electronic prescription attempts generated alerts. Clinicians accepted 9.2% of drug interaction alerts and 23.0% of allergy alerts. High-severity interactions accounted for most alerts (61.6%); clinicians accepted high-severity alerts slightly more often than moderate- or low-severity interaction alerts (10.4%, 7.3%, and 7.1%, respectively; P < .001). Clinicians accepted 2.2% to 43.1% of high-severity interaction alerts, depending on the classes of interacting medications. In multivariable analyses, we found no difference in alert acceptance among clinicians of different specialties (P = .16). Clinicians were less likely to accept a drug interaction alert if the patient had previously received the alerted medication (odds ratio, 0.03; 95% confidence interval, 0.03-0.03).

Conclusion Clinicians override most medication alerts, suggesting that current medication safety alerts may be inadequate to protect patient safety.

Shahid N. Shah

Shahid N. Shah

Shahid Shah is an internationally recognized enterprise software guru that specializes in digital health with an emphasis on e-health, EHR/EMR, big data, iOT, data interoperability, med device connectivity, and bioinformatics.


As a thought leader in the healthcare IT space I get a lot of emails that blame physicians for not changing their behavior and not more more easily accepting information technology. The IT solutions …

Did you find this useful?

Medigy Innovation Network

Connecting innovation decision makers to authoritative information, institutions, people and insights.

Medigy Logo

The latest News, Insights & Events

Medigy accurately delivers healthcare and technology information, news and insight from around the world.

The best products, services & solutions

Medigy surfaces the world's best crowdsourced health tech offerings with social interactions and peer reviews.


© 2023 Netspective Media LLC. All Rights Reserved.

Built on Jan 17, 2023 at 9:26am